Right and yet wrong: a politico-economic perspective on Germany's early COVID-19 policy

Applying a spatio-temporal endemic–epidemic forecasting model, we evaluate different perspectives on the adequacy of COVID-19 containment policies. Using Germany's early containment policy as an example, we show that containment policies judged as rational based on the real-time perspective of policymakers may be deemed unnecessary or ineffective in ex-post evaluations. We also demonstrate that one-size-fits-all policies implemented in Germany early in the pandemic are likely suboptimal. © 2023 Regional Studies Association.

National lockdowns in England: The same restrictions for all, but do the impacts on COVID-19 mortality risks vary geographically?

Quantifying the impact of lockdowns on COVID-19 mortality risks is an important priority in the public health fight against the virus, but almost all of the existing research has only conducted macro country-wide assessments or limited multi-country comparisons. In contrast, the extent of within-country variation in the impacts of a nation-wide lockdown is yet to be thoroughly investigated, which is the gap in the knowledge base that this paper fills. Our study focuses on England, which was subject to 3 national lockdowns between March 2020 and March 2021. We model weekly COVID-19 mortality counts for the 312 Local Authority Districts in mainland England, and our aim is to understand the impact that lockdowns had at both a national and a regional level. Specifically, we aim to quantify how long after the implementation of a lockdown do mortality risks reduce at a national level, the extent to which these impacts vary regionally within a country, and which parts of England exhibit similar impacts. As the spatially aggregated weekly COVID-19 mortality counts are small in size we estimate the spatio-temporal trends in mortality risks with a Poisson log-linear smoothing model that borrows strength in the estimation between neighbouring data points. Inference is based in a Bayesian paradigm, using Markov chain Monte Carlo simulation. Our main findings are that mortality risks typically begin to reduce between 3 and 4 weeks after lockdown, and that there appears to be an urban-rural divide in lockdown impacts.

Spatio-temporal small area surveillance of the COVID-19 pandemic.

The emergence of COVID-19 requires new effective tools for epidemiological surveillance. Spatio-temporal disease mapping models, which allow dealing with small units of analysis, are a priority in this context. These models provide geographically detailed and temporally updated overviews of the current state of the pandemic, making public health interventions more effective. These models also allow estimating epidemiological indicators highly demanded for COVID-19 surveillance, such as the instantaneous reproduction number R t , even for small areas. In this paper, we propose a new spatio-temporal spline model particularly suited for COVID-19 surveillance, which allows estimating and monitoring R t for small areas. We illustrate our proposal on the study of the disease pandemic in two Spanish regions. As a result, we show how tourism flows have shaped the spatial distribution of the disease in these regions. In these case studies, we also develop new epidemiological tools to be used by regional public health services for small area surveillance.

Environmental risk factors of airborne viral transmission: Humidity, Influenza and SARS-CoV-2 in the Netherlands.

OBJECTIVE: The relationship between specific humidity and influenza/SARS-CoV-2 in the Netherlands is evaluated over time and at regional level. DESIGN: Parametric and non-parametric correlation coefficients are calculated to quantify the relationship between humidity and influenza, using five years of weekly data. Bayesian spatio-temporal models-with a Poisson and a Gaussian likelihood-are estimated to find the relationship between regional humidity and the daily cases of SARS-CoV-2 in the municipalities and provinces of the Netherlands. RESULTS: An inverse (negative) relationship is observed between specific humidity and the incidence of influenza between 2015 and 2019. The space-time analysis indicates that an increase of specific humidity of one gram of water vapor per kilogram of air (1 g/kg) is related to a reduction of approximately 5% in the risk of COVID-19 infections. CONCLUSIONS: The increase in humidity during the outbreak of the SARS-CoV-2 in the Netherlands may have helped to reduce the risk of regional COVID-19 infections. Policies that lead to an increase in household specific humidity to over 6g/Kg will help reduce the spread of respiratory viruses such as influenza and SARS-CoV-2.